Although it is not known whether or not other not known interactions are transpiring in the receptor that contribute to its effects, the receptor performs a task to be a detrimental down regulator of endogenous opiate levels through scavenging action. This drug-receptor interaction presents an alternative to manipulation on the classical opiate pat
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Though the opiate receptor relies on G protein coupling for signal transduction, this receptor was found to employ arrestin activation for internalization in the receptor. Normally, the receptor promoted no other signaling cascades (fifty nine) Modifications of conolidine have resulted in variable improvement in binding efficacy. This binding event
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